A propensity-score-matched analysis of laparoscopic vs open surgery for rectal cancer in a population-based study / P. Manchon-Walsh, L. Aliste, S. Biondo, E. Espin, M. Pera, E. Targarona, N. Pallarès, R. Vernet, J. A. Espinàs, A. Guarga, J. M. Borràs
Creator: Manchon-Walsh, Paula [autor].
Creators: Aliste, Luisa | Biondo, Sebastián [autor] | Espin, Eloy [autor] | Pera Román, Miguel [autor] | Targarona, Eduardo M [autor] | Pallarès, Natàlia [autor] | Vernet Bellet, Raül, https://orcid.org/0000-0002-1964-6974 [autor] | Espinàs Piñol, Josep Alfons [autor] | Guarga, Alex [autor] | Borràs Andrés, Josep Maria [autor] | Escola Universitària d'Infermeria i Teràpia Ocupacional de Terrassa | Institut d'Investigació Biomèdica de Bellvitge.
Material type: ArticleContent type: text Media type: informàtic Carrier type: recurs en línia New identifier: doi:: 10.1111/codi.14545Subject(s): Càncer de recte | Laparoscòpia | Cirurgia | Professors -- EUIT | Catalunya | Càncer colorectal | Colorectal cancer | Laparoscopy | Surgery | Statistics | Spain | CataloniaGenre/Form: info:eu-repo/semantics/article | info:eu-repo/semantics/postprintVersion | info:eu-repo/semantics/postprintVersionOnline resources: Enllaç permanent | Accés lliure pdf | Accés lliure (adreça alternativa) | Sol·licitar article a la Biblioteca | Dimensions: Cites | Almetric: Cites | Google Acadèmic: Cites | PubMed: Cites In: Colorectal Disease 2019;21(4):441-450Summary: Abstract Aim The oncological risk/benefit trade‐off for laparoscopy in rectal cancer is controversial. Our aim was to compare laparoscopic vs open surgery for resection of rectal cancer, using unselected data from the public healthcare system of Catalonia (Spain). Methods This was a multicentre retrospective cohort study of all patients who had surgery with curative intent for primary rectal cancer at Catalonian public hospitals from 2011 to 2012. We obtained follow‐up data for up to 5 years. To minimize the differences between the two groups, we performed propensity score matching on baseline patient characteristics. We used multivariate Cox proportional hazards regression analyses to assess locoregional relapse at 2 years and death at 2 and 5 years. Results Of 1513 patients with Stage I-III rectal cancer, 933 (61.7%) had laparoscopy (conversion rate 13.2%). After applying our propensity score matching strategy (2:1), 842 laparoscopy patients were matched to 517 open surgery patients. Multivariate Cox analysis of death at 2 years [hazard ratio (HR) 0.65, 95% CI 0.48, 0.87; P = 0.004] and 5 years (HR 0.61, 95% CI 0.5, 0.75; P < 0.001) and of local relapse at 2 years (HR 0.44, 95% CI 0.27, 0.72; P = 0.001) showed laparoscopy to be an independent protective factor compared with open surgery. Conclusions Laparoscopy results in lower locoregional relapse and long‐term mortality in rectal cancer in unselected patients with all‐risk groups included. Studies using long‐term follow‐up of cohorts and unselected data can provide information on clinically relevant outcomes to supplement randomized controlled trials.Item type | Current library | Collection | Call number | URL | Status | Notes | Date due | Barcode | |
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Journal article | Dipòsit Digital EUIT Biblioteca | Fitxer informàtic | Exclòs de préstec | 0010173102272 | |||||
Journal | Escola Universitària d'Infermeria i Teràpia Ocupacional de Terrassa Internet | En línia | Text complet | Not for loan | Alguns articles són en accés lliure | 0001017285404 | |||
Journal article | Escola Universitària d'Infermeria i Teràpia Ocupacional de Terrassa Biblioteca | Fitxer informàtic | ART-861 (Browse shelf(Opens below)) | Text complet | Not for loan | 0001017281536 |
This study has been partially funded by the Agència de Gestió d'Ajuts Universitaris i de Recerca, (AGAUR, 2017SGR735).
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© 2018 The Association of Coloproctology of Great Britain and Ireland
MÈTRIQUES
Journal Impact Factor (Journal Citation Reports) • Any: 2017 (És l'últim any del que es disposen dades)
• Factor d'impacte: 2.778
• Categoria: GASTROENTEROLOGY & HEPATOLOGY
• Posició de la revista: 49/80
• Quartil: Q3 • Categoria: SURGERY
• Posició de la revista: 49/200 • Quartil: Q1
CiteScore (Scopus Journal Metrics) • Any: 2017
• Factor d'impacte: 1.86
• Categoria: Medicine - Gastroenterology
• Posició de la revista: #58/128
• Percentil: 54th Almetric https://wiley.altmetric.com/details/53185782
Bases de dades on s'indexa Science Citation Index Expanded, Scopus, Academic Search Premier, Agricultural & Environmental Science Database, EMBASE, MEDLINE
Descripció del recurs: 21 gener 2019
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